Author's response to reviews Title: Gastroprotective effect of Desmosdumotin C isolated from Mitrella Kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide and anti-helicobacter pylori activity Authors:

نویسندگان

  • Heyam M A Sidahmed
  • Ainnul Azizan
  • Najihah M Hashim
  • Jamuna Vadivelu
چکیده

Heyam M A Sidahmed ([email protected]) Ainnul Azizan ([email protected]) Syam Mohan ([email protected]) Mahmood A Abdulla ([email protected]) Siddig I Abdelwahab ([email protected]) Manal M E Taha ([email protected]) A. Hamid A. Hadi ([email protected]) Kamal A Ketuly ([email protected]) Najihah M Hashim ([email protected]) Mun F Loke ([email protected]) Jamuna Vadivelu ([email protected])

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Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide, and anti-Helicobacter pylori activity

BACKGROUND Mitrella kentii (M. kentii) (Bl.) Miq, is a tree-climbing liana that belongs to the family Annonaceae. The plant is rich with isoquinoline alkaloids, terpenylated dihydrochalcones and benzoic acids and has been reported to possess anti-inflammatory activity. The purpose of this study is to assess the gastroprotective effects of desmosdumotin C (DES), a new isolated bioactive compound...

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تاریخ انتشار 2009